TANC2 Foundation

Frequently Asked Questions

Find answers to common questions about TANC2-Related Disorders.

What is TANC2?

TANC2 is a protein-coding gene that plays a critical role in brain development and synaptic function, encoding a scaffolding protein essential for proper neuronal connections.

What does a mutation on the Gene TANC2 cause in humans?

TANC2 mutations cause a spectrum of neurodevelopmental conditions known as TANC2-Related Disorders, including autism (50% of cases), intellectual disability, language delays (88%), motor delays, and seizures. Some individuals may also experience psychiatric conditions.

Is there a treatment?

No, at the moment there is no treatment.

Where can I get more information?

You can join our to connect for information.

Our Mission

TANC2 Foundation is a nonprofit organization dedicated to supporting families affected by TANC2-Related Disorders (TRD). Our mission is to provide support, education, and awareness to the TANC2 community while promoting research to better understand and develop treatments.